Angèle Nalbandian Selected Research

Valosin Containing Protein

2/2017	Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy.
1/2017	Myogenic differentiation of VCP disease-induced pluripotent stem cells: A novel platform for drug discovery.
5/2015	In vitro studies in VCP-associated multisystem proteinopathy suggest altered mitochondrial bioenergetics.
2/2015	Targeted excision of VCP R155H mutation by Cre-LoxP technology as a promising therapeutic strategy for valosin-containing protein disease.
2/2015	Global gene expression profiling in R155H knock-in murine model of VCP disease.
1/2015	A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy.
1/2015	Rapamycin and chloroquine: the in vitro and in vivo effects of autophagy-modifying drugs show promising results in valosin containing protein multisystem proteinopathy.
1/2015	Early-onset Alzheimers and cortical vision impairment in a woman with valosin-containing protein disease associated with 2 APOE ε4/APOE ε4 genotype.
3/2014	Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease.
2/2014	Cytokine profiling in patients with VCP-associated disease.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Angèle Nalbandian Research Topics

Disease

13	Frontotemporal Dementia (Semantic Dementia) 05/2015 - 10/2010
12	Muscular Diseases (Myopathy) 02/2017 - 10/2010
12	Osteitis Deformans (Paget's Disease of Bone) 05/2015 - 10/2010
6	Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal Dementia 02/2014 - 10/2010
5	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2017 - 03/2014
5	Proteostasis Deficiencies 01/2017 - 02/2014
4	Muscle Weakness 01/2017 - 02/2013
4	Nonaka type Distal myopathy 01/2015 - 01/2012
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 03/2014 - 11/2011
3	Neoplasms (Cancer) 06/2012 - 10/2005
2	Inflammation (Inflammations) 02/2017 - 10/2015
2	Atrophy 01/2017 - 01/2013
2	Neoplasm Metastasis (Metastasis) 01/2006 - 10/2005
2	Prostatic Neoplasms (Prostate Cancer) 01/2006 - 10/2005
1	Arthritis (Polyarthritis) 10/2015
1	Lupus Nephritis 10/2015
1	Angelman Syndrome (Syndrome, Angelman) 04/2015
1	Body Weight (Weight, Body) 02/2015
1	Alzheimer Disease (Alzheimer's Disease) 01/2015
1	Amyloid Plaque 01/2015
1	Cachexia 02/2014
1	Hypertrophy 01/2013
1	Muscular Atrophy (Muscle Atrophy) 01/2013
1	Neuromuscular Diseases (Neuromuscular Disease) 01/2013
1	Pain (Aches) 11/2011
1	Infertility (Sterility) 09/2003

Drug/Important Bio-Agent (IBA)

16	Valosin Containing ProteinIBA 02/2017 - 10/2010
4	UbiquitinIBA 04/2015 - 01/2013
2	LipidsIBA 01/2015 - 03/2014
2	Biological ProductsIBA 06/2012 - 10/2005
2	Nerve Growth Factor Receptor (Nerve Growth Factor Receptor, Low Affinity)IBA 01/2006 - 10/2005
1	N- (1,2,3,5,6,7- hexahydro- S- indacen- 4- ylcarbamoyl)- 4- (2- hydroxy- 2- propanyl)- 2- furansulfonamideIBA 02/2017
1	InflammasomesIBA 02/2017
1	Proteins (Proteins, Gene)FDA Link 02/2017
1	Caspase 1 (ICE Protease)IBA 02/2017
1	Interleukin-18 (Interleukin 18)IBA 02/2017
1	NLR ProteinsIBA 02/2017
1	Complement Receptors (Complement Receptor)IBA 10/2015
1	AutoantibodiesIBA 10/2015
1	Complement System Proteins (Complement)IBA 10/2015
1	Immunoglobulins (Immunoglobulin)IBA 10/2015
1	Pharmaceutical PreparationsIBA 05/2015
1	coenzyme Q10 (CoQ10)IBA 04/2015
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 04/2015
1	Corn Oil (Oil, Corn)IBA 02/2015
1	Tamoxifen FDA LinkGeneric 02/2015
1	Amyloidogenic ProteinsIBA 01/2015
1	Chloroquine (Aralen)FDA LinkGeneric 01/2015
1	MTOR InhibitorsIBA 01/2015
1	Apolipoproteins E (ApoE)IBA 01/2015
1	Sirolimus (Rapamycin)FDA Link 01/2015
1	CytokinesIBA 02/2014
1	Epidermal Growth Factor (EGF)IBA 02/2014
1	Therapeutic UsesIBA 01/2013
1	Alkaline PhosphataseIBA 11/2011
1	ATPases Associated with Diverse Cellular ActivitiesIBA 11/2011
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2006
1	Matrix Metalloproteinases (MMPs)IBA 01/2006
1	Collagenases (Collagenase)FDA Link 01/2006
1	Collagen Type IV (Type IV Collagen)IBA 01/2006
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 01/2006
1	Peptide Hydrolases (Proteases)FDA Link 01/2006
1	Plasminogen Activators (Plasminogen Activator)IBA 01/2006
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2006
1	DNA (Deoxyribonucleic Acid)IBA 10/2005
1	retinoic acid receptor betaIBA 10/2005
1	RetinoidsIBA 10/2005
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2003

Therapy/Procedure

2	Therapeutics 01/2015 - 06/2012
1	Endurance Training 01/2013